CAR t therapy takes on lupus and other autoimmune diseases

NCT ID NCT06462144

First seen Feb 01, 2026 · Last updated May 08, 2026 · Updated 11 times

Summary

This early-phase trial tested a single dose of IMPT-514, a personalized CAR T cell therapy, in 3 adults with active, treatment-resistant lupus, vasculitis, or inflammatory myopathy. The main goal was to check safety and side effects. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • The Affiliated Hospital Of Xuzhou Medical University

    Xuzhou, Jiangsu, 221004, China

  • The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

    Nanjing, Jiangsu, 210008, China

  • Zhongshan Hospital Fudan University.

    Shanghai, Shanghai Municipality, 200032, China

Conditions

Explore the condition pages connected to this study.