New heart pump aims to make risky artery procedures safer

NCT ID NCT05334784

ENROLLING_BY_INVITATION Disease control Sponsor: Abiomed Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests the Impella ECP, a temporary heart pump, in 856 adults undergoing high-risk angioplasty (a procedure to open blocked heart arteries). The pump is inserted before the procedure to help keep blood flowing. Researchers will track major heart and brain complications, bleeding, and device-related issues for 30 days after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Impella ECP device
What this could lead to: If successful, this could provide a safer way to perform high-risk angioplasty in patients with complex heart disease.
What could go wrong: This is an early-stage study without a comparison group, so results may not prove the device is better than standard care. Risks include bleeding, vascular complications, and device-related injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIGH RISK PERCUTANEOUS CORONARY INTERVENTION

Contacts and locations

Locations

AdventHealth - Tampa

Tampa, Florida, 33613, United States
Adventist Health Glendale

Glendale, California, 91206, United States
Arkansas Heart Hospital

Little Rock, Arkansas, 72211, United States
Ascension St. John Hospital

Detroit, Michigan, 48236, United States
Baylor Scott & White The Heart Hospital Plano

Plano, Texas, 75093, United States
Buffalo General

Buffalo, New York, 14203, United States
CUMC/ New York Presbyterian Hospital

New York, New York, 10032, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Hackensack University Medical Ctr

Hackensack, New Jersey, 07601, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Keck Hospital of USC

Los Angeles, California, 90033, United States
Lenox Hill Hospital

New York, New York, 10075, United States
Loma Linda University Medical Center

San Bernardino, California, 92354, United States
Manatee Memorial Hospital

Bradenton, Florida, 34208, United States
Methodist Hospital - San Antonio

San Antonio, Texas, 78229, United States
Morristown Medical Center

Morristown, New Jersey, 07960, United States
New Mexico Heart Institute

Albuquerque, New Mexico, 87102, United States
North Florida Regional Medical Center

Gainesville, Florida, 34208, United States
Ochsner Foundation Hospital

New Orleans, Louisiana, 70121, United States
Oklahoma Heart Hospital - South

Oklahoma City, Oklahoma, 73135, United States
Pima Heart & Vascular

Tucson, Arizona, 85712, United States
Providence St. Patrick

Missoula, Montana, 59802, United States
Providence St. Vincent Med Center

Portland, Oregon, 97225, United States
Sentara Norfolk Health System

Norfolk, Virginia, 23507, United States
Spectrum Health

Grand Rapids, Michigan, 49503, United States
St. Cloud (CentraCare)

Saint Cloud, Minnesota, 56303, United States
St. Joseph's Medical Center - Phoenix

Phoenix, Arizona, 85013, United States
Texas Health Presbyterian Hospital Dallas

Dallas, Texas, 75231, United States
The Valley Hospital

Ridgewood, New Jersey, 07450, United States
TriStar Centennial Medical Center

Nashville, Tennessee, 37203, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
West Virginia University Hospital

Morgantown, West Virginia, 26506, United States

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