New drug duo aims to shrink breast tumors before surgery

NCT ID NCT07410559

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking two drugs (imlunestrant and abemaciclib) before surgery can shrink tumors in people with a common type of breast cancer (ER+/HER2-). About 189 women aged 18-75 with early-stage breast cancer will join. The treatment is guided by a marker called Ki67, which shows how fast cancer cells grow. The goal is to see if this approach improves response and reduces cancer before surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

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