New drug duo aims to shrink breast tumors before surgery

NCT ID NCT07410559

First seen Feb 15, 2026 · Last updated Jun 12, 2026 · Updated 23 times

Summary

This study tests whether taking two drugs (imlunestrant and abemaciclib) before surgery can shrink tumors in people with a common type of breast cancer (ER+/HER2-). About 189 women aged 18-75 with early-stage breast cancer will join. The treatment is guided by a marker called Ki67, which shows how fast cancer cells grow. The goal is to see if this approach improves response and reduces cancer before surgery.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.