Radiation boost tested to help immune system fight advanced head and neck cancer

NCT ID NCT05721755

Summary

This study is for adults whose head and neck cancer has spread to a few other places in the body. It tests if adding a targeted course of radiation therapy to standard immunotherapy helps patients live longer than immunotherapy alone. About 290 participants will be randomly assigned to receive either the combination treatment or just the immunotherapy.

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Contacts and locations

Locations

  • Ascension Saint Mary's Hospital

    Rhinelander, Wisconsin, 54501, United States

  • Ascension Saint Michael's Hospital

    Stevens Point, Wisconsin, 54481, United States

  • Aspirus Cancer Care - Wisconsin Rapids

    Wisconsin Rapids, Wisconsin, 54494, United States

  • Aspirus Regional Cancer Center

    Wausau, Wisconsin, 54401, United States

  • Carle Cancer Center

    Urbana, Illinois, 61801, United States

  • Carle Physician Group-Effingham

    Effingham, Illinois, 62401, United States

  • Carle Physician Group-Mattoon/Charleston

    Mattoon, Illinois, 61938, United States

  • Carle at The Riverfront

    Danville, Illinois, 61832, United States

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Freeman Health System

    Joplin, Missouri, 64804, United States

  • Gundersen Lutheran Medical Center

    La Crosse, Wisconsin, 54601, United States

  • Highland Hospital

    Rochester, New York, 14620, United States

  • Iowa Methodist Medical Center

    Des Moines, Iowa, 50309, United States

  • Langlade Hospital and Cancer Center

    Antigo, Wisconsin, 54409, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Mercy Hospital

    Cedar Rapids, Iowa, 52403, United States

  • Mission Cancer and Blood - Ankeny

    Ankeny, Iowa, 50023, United States

  • Mission Cancer and Blood - Des Moines

    Des Moines, Iowa, 50309, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Moffitt Cancer Center - McKinley Campus

    Tampa, Florida, 33612, United States

  • Moffitt Cancer Center-International Plaza

    Tampa, Florida, 33607, United States

  • Oncology Associates at Mercy Medical Center

    Cedar Rapids, Iowa, 52403, United States

  • ProHealth D N Greenwald Center

    Mukwonago, Wisconsin, 53149, United States

  • ProHealth Oconomowoc Memorial Hospital

    Oconomowoc, Wisconsin, 53066, United States

  • Providence Newberg Medical Center

    Newberg, Oregon, 97132, United States

  • Providence Saint Vincent Medical Center

    Portland, Oregon, 97225, United States

  • Saint Luke's Cancer Institute - Boise

    Boise, Idaho, 83712, United States

  • Saint Luke's Cancer Institute - Fruitland

    Fruitland, Idaho, 83619, United States

  • Saint Luke's Cancer Institute - Meridian

    Meridian, Idaho, 83642, United States

  • Saint Luke's Cancer Institute - Nampa

    Nampa, Idaho, 83686, United States

  • Saint Luke's Cancer Institute - Twin Falls

    Twin Falls, Idaho, 83301, United States

  • Sands Cancer Center

    Canandiaqua, New York, 14424, United States

  • Sanford Bismarck Medical Center

    Bismarck, North Dakota, 58501, United States

  • Sanford Broadway Medical Center

    Fargo, North Dakota, 58122, United States

  • Sanford Cancer Center Oncology Clinic

    Sioux Falls, South Dakota, 57104, United States

  • Sanford Joe Lueken Cancer Center

    Bemidji, Minnesota, 56601, United States

  • Sanford Roger Maris Cancer Center

    Fargo, North Dakota, 58122, United States

  • Sanford USD Medical Center - Sioux Falls

    Sioux Falls, South Dakota, 57117-5134, United States

  • Stony Brook University Medical Center

    Stony Brook, New York, 11794, United States

  • UH Seidman Cancer Center at Lake Health Mentor Campus

    Mentor, Ohio, 44060, United States

  • UH Seidman Cancer Center at UH Avon Health Center

    Avon, Ohio, 44011, United States

  • UW Cancer Center at ProHealth Care

    Waukesha, Wisconsin, 53188, United States

  • University of Illinois

    Chicago, Illinois, 60612, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • VCU Massey Cancer Center at Stony Point

    Richmond, Virginia, 23235, United States

  • Virginia Commonwealth University/Massey Cancer Center

    Richmond, Virginia, 23298, United States

  • Wilmot Cancer Institute Radiation Oncology at Greece

    Rochester, New York, 14606, United States

  • Wilmot Cancer Institute at Webster

    Webster, New York, 14580, United States

Conditions

Explore the condition pages connected to this study.