Sepsis Patients' immune paralysis may raise pneumonia risk
NCT ID NCT01135277
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at 50 ICU patients to see if sepsis causes immune suppression that increases the risk of ventilator-associated pneumonia. Researchers compared septic patients to non-septic ones by measuring immune markers in blood and lung fluid over five days. The goal was to understand how sepsis affects the body's ability to fight infections, which could lead to better prevention strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could help identify why sepsis patients are more prone to secondary infections, potentially guiding future treatments.
- What could go wrong
- This is a small, observational study with only 50 participants, so findings may not apply broadly. It does not test a treatment, so direct patient benefits are not expected.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Ohio State University
Columbus, Ohio, 43221, United States
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Other studies related to the condition(s) this trial covers.
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