Can a tumor-zapping procedure also wake up the immune system?
NCT ID NCT04892810
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This study looks at how two heat-based procedures — radiofrequency ablation and microwave ablation — affect the immune system in people with small liver cancers. Researchers will take blood samples and tissue biopsies before and after treatment to track changes in immune cells. The goal is to understand whether one method triggers a stronger immune response than the other.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- percutaneous ablation (radiofrequency or microwave)
- What this could lead to
- If the immune response differs between the two ablation methods, it could point toward ways to boost the body's own fight against liver cancer.
- What could go wrong
- This is a very small, early observational study — it is not designed to test a treatment's effectiveness, and any immune changes seen may not lead to better outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
CHU Grenoble Alpes
Grenoble, 38043, France
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