Immune insights could pave way for new AML therapies

NCT ID NCT06279572

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is collecting blood and bone marrow samples from 80 adults with acute myeloid leukemia (AML) who are starting treatment with azacitidine plus venetoclax. Researchers want to understand how the immune system responds to this chemotherapy combination. The goal is to find clues that could help develop future T-cell based immunotherapies for AML.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new immune-based treatments for acute myeloid leukemia.

What could go wrong

This is an early observational study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all AML patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    NOT_YET_RECRUITING

    Scottsdale, Arizona, 85259, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic in Florida

    RECRUITING

    Jacksonville, Florida, 32224-9980, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic in Rochester

    NOT_YET_RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact