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Study probes immune changes after heat ablation of lung tumors

NCT ID NCT03960021

Terminated Knowledge-focused Sponsor: Institut Bergonié Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how radiofrequency ablation (RFA), a procedure that uses heat to destroy tumors, affects the immune system in people with lung metastases from colorectal cancer. Researchers measured immune cells in tumor samples and blood before and after RFA in 20 participants. The study was terminated early, so the findings are limited, but the goal was to better understand the immune response triggered by this treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiofrequency ablation (RFA)
What this could lead to
If successful, this could help doctors understand how RFA might boost the body's immune response against cancer, potentially improving future treatments.
What could go wrong
This was a small, early-stage study that was terminated, so results are limited. The findings may not apply to all patients or lead to direct treatment changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal cancer metastatic neoplasm neoplasm Neoplastic Cells, Circulating

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRCULATING TUMOR CELL COLO-RECTAL CANCER IMMUNE EVASION, TUMOR NEOPLASTIC CELLS, CIRCULATING PULMONARY METASTASIS

Contacts and locations

Locations

  • Institut Bergonie

    Bordeaux, 33076, France

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