Melanoma drug IMLYGIC under safety watch for herpes risk

NCT ID NCT02910557

First seen Nov 15, 2025 · Last updated May 13, 2026 · Updated 22 times

Summary

This study followed 187 adults with melanoma who were treated with IMLYGIC, a virus-based therapy. Researchers wanted to see if the virus spreads to patients' close contacts or healthcare providers, and to check for long-term side effects over 5 years. The goal was to better understand the real-world safety of this treatment.

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Contacts and locations

Locations

  • Allegheny Health Network

    Pittsburgh, Pennsylvania, 15224, United States

  • Cheltenham General Hospital

    Cheltenham, GL53 7AN, United Kingdom

  • Churchill Hospital

    Oxford, OX3 7LJ, United Kingdom

  • Corazon United States of America, LLC doing business as Life Clinical Trials

    Coral Springs, Florida, 33076, United States

  • Guys Hospital

    London, SE1 9RT, United Kingdom

  • Intermountain Medical Center

    Murray, Utah, 84107, United States

  • Jefferson City Medical Group PC

    Jefferson City, Missouri, 65109, United States

  • Kantonsspital Graubuenden

    Chur, 7000, Switzerland

  • Landeskrankenhaus Salzburg

    Salzburg, 5020, Austria

  • Medizinische Universitaet Graz

    Graz, 8036, Austria

  • Mercy Medical Center

    Baltimore, Maryland, 21202, United States

  • Musgrove Park Hospital

    Taunton, TA1 5DA, United Kingdom

  • Ordensklinikum Linz Elisabethinen

    Linz, 4020, Austria

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Royal Marsden Hospital

    London, SW3 6JJ, United Kingdom

  • Sheba Medical Center

    Ramat Gan, 5262000, Israel

  • TriHealth Cancer Institute - Kenwood

    Cincinnati, Ohio, 45242, United States

  • Universitaetsklinikum Sankt Poelten

    Sankt Pölten, 3100, Austria

  • Universitaetsspital Basel

    Basel, 4052, Switzerland

  • Universitaetsspital Zuerich

    Zuerich Flughafen, 8058, Switzerland

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Tennessee Medical Center

    Knoxville, Tennessee, 37920, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.