Melanoma drug IMLYGIC: how safe is it for family and doctors?

NCT ID NCT02910557

First seen Nov 15, 2025 · Last updated May 17, 2026 · Updated 23 times

Summary

This study followed 187 melanoma patients treated with IMLYGIC to see if the virus in the drug could cause herpetic infections in patients, their close contacts, and healthcare providers. Researchers checked for the drug's DNA over up to 5 years. The goal was to understand long-term safety and infection risks in real-world use.

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Contacts and locations

Locations

  • Allegheny Health Network

    Pittsburgh, Pennsylvania, 15224, United States

  • Cheltenham General Hospital

    Cheltenham, GL53 7AN, United Kingdom

  • Churchill Hospital

    Oxford, OX3 7LJ, United Kingdom

  • Corazon United States of America, LLC doing business as Life Clinical Trials

    Coral Springs, Florida, 33076, United States

  • Guys Hospital

    London, SE1 9RT, United Kingdom

  • Intermountain Medical Center

    Murray, Utah, 84107, United States

  • Jefferson City Medical Group PC

    Jefferson City, Missouri, 65109, United States

  • Kantonsspital Graubuenden

    Chur, 7000, Switzerland

  • Landeskrankenhaus Salzburg

    Salzburg, 5020, Austria

  • Medizinische Universitaet Graz

    Graz, 8036, Austria

  • Mercy Medical Center

    Baltimore, Maryland, 21202, United States

  • Musgrove Park Hospital

    Taunton, TA1 5DA, United Kingdom

  • Ordensklinikum Linz Elisabethinen

    Linz, 4020, Austria

  • Rambam Medical Center

    Haifa, 3109601, Israel

  • Royal Marsden Hospital

    London, SW3 6JJ, United Kingdom

  • Sheba Medical Center

    Ramat Gan, 5262000, Israel

  • TriHealth Cancer Institute - Kenwood

    Cincinnati, Ohio, 45242, United States

  • Universitaetsklinikum Sankt Poelten

    Sankt Pölten, 3100, Austria

  • Universitaetsspital Basel

    Basel, 4052, Switzerland

  • Universitaetsspital Zuerich

    Zuerich Flughafen, 8058, Switzerland

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Tennessee Medical Center

    Knoxville, Tennessee, 37920, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.