Cancer drug repurposed to shrink NF1 skin bumps in early trial

NCT ID NCT07102394

First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 26 times

Summary

This early-stage study tests if a drug called IMLYGIC, already used for certain skin cancers, can safely treat painful or disfiguring skin bumps (cutaneous neurofibromas) in adults with NF1. Ten participants will receive up to 4 cycles of injections directly into their tumors. The main goals are to see if the treatment is feasible and tolerable, not yet to cure the condition.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.