New pill combo shows promise in shrinking breast tumors before surgery

NCT ID NCT07410559

First seen Feb 15, 2026 · Last updated Apr 28, 2026 · Updated 13 times

Summary

This study tests two drugs (imlunestrant and abemaciclib) given before surgery to shrink tumors in people with a common type of breast cancer (ER-positive, HER2-negative). About 189 women aged 18-75 will take these pills for a few weeks, and doctors will check how well the tumor responds using a marker called Ki67. The goal is to see if this combination can reduce or eliminate cancer before the operation, potentially leading to better long-term outcomes.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.