Cream and radiation combo tackles rare skin cancer
NCT ID NCT05838599
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests whether combining a topical immune-boosting cream (imiquimod) with local radiation can better treat mycosis fungoides, a rare skin lymphoma. About 25 adults with stable but active disease who have tried at least one other therapy will receive the cream for 5 weeks, then two doses of radiation. The study primarily checks safety and skin lesion response at 8 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
imiquimod cream and radiation therapy
What this could lead to
If it works, this could point toward a more effective combination treatment for mycosis fungoides skin lesions.
What could go wrong
This is a very early, small trial (25 people) testing safety and initial effectiveness. The combination may not work better than radiation alone, and side effects are unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Northwestern University Department of Dermatology
RECRUITINGChicago, Illinois, 60611, United States
Contact