Cancer drug shows promise in taming rare blood disorder

NCT ID NCT00044304

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests whether the drug imatinib (Gleevec) can safely lower high levels of eosinophils (a type of white blood cell) in people with a rare condition called hypereosinophilic syndrome. About 70 participants with the myeloid form or those who didn't respond to steroids will take imatinib daily, with doses adjusted based on response. The goal is to bring eosinophil counts to normal and reduce organ damage, while allowing some patients to eventually stop the drug.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.