Scientists reprogram leukemia cells to fight themselves

NCT ID NCT02483312

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests a new approach for people with acute myeloid leukemia (AML) that has returned or is likely to return, and who cannot have a bone marrow transplant. Researchers take a patient's own leukemia cells, modify them in the lab to produce a protein called IL-12, and then give them back. The goal is to see if this treatment is safe and can help control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Princess Margaret Centre Centre

    Toronto, Ontario, M5G 2M9, Canada