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Head-to-head trial aims to find best way to save sight in IIH patients

NCT ID NCT07440277

Recruiting now Disease control Sponsor: University of Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common procedures—CSF shunting and dural venous sinus stenting—to see which better preserves vision in adults with idiopathic intracranial hypertension (IIH) who are at risk of permanent sight loss. About 80 participants will be randomly assigned to one of the two procedures and followed for two years. The goal is to determine which treatment is more effective and cost-effective for saving vision.

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Conditions

The condition(s) this trial relates to.

Constriction, Pathologic optic papillitis pseudotumor cerebri vision disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IIH - IDIOPATHIC INTRACRANIAL HYPERTENSION

Contacts and locations

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, United Kingdom

  • Bristol Eye Hospital

    NOT_YET_RECRUITING

    Bristol, United Kingdom

  • King's College Hospital

    RECRUITING

    London, United Kingdom

  • Leeds General Infirmary

    RECRUITING

    Leeds, United Kingdom

  • National Hospital for Neurology and Neurosurgery

    RECRUITING

    London, United Kingdom

  • Princess Alexandra Eye Pavillion

    RECRUITING

    Edinburgh, United Kingdom

  • Queen Elizabeth University Hospital

    RECRUITING

    Glasgow, United Kingdom

  • Queen's Medical Centre

    RECRUITING

    Nottingham, United Kingdom

  • Royal Hull Infirmary

    RECRUITING

    Hull, United Kingdom

  • Royal Victoria Infirmary

    RECRUITING

    Newcastle, United Kingdom

  • Southampton General Hospital

    RECRUITING

    Southampton, United Kingdom

  • Southmead Hospital

    NOT_YET_RECRUITING

    Bristol, United Kingdom

  • Sunderland Eye Infirmary

    RECRUITING

    Sunderland, United Kingdom

  • The Queen Elizabeth Hospital

    RECRUITING

    Birmingham, United Kingdom

  • University Hospital of Wales

    RECRUITING

    Cardiff, United Kingdom

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