Brain pressure breakthrough: which surgery saves sight best?

NCT ID NCT07440277

First seen Mar 03, 2026 · Last updated Apr 30, 2026 · Updated 7 times

Summary

This study compares two common surgeries—CSF shunting and dural venous sinus stenting—to see which better preserves vision in people with idiopathic intracranial hypertension (IIH) who are at risk of blindness. About 80 adults with IIH and severe papilledema will be randomly assigned to one procedure and followed for two years. The goal is to find the most effective and cost-effective way to protect eyesight.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, United Kingdom

    Contact

  • Bristol Eye Hospital

    NOT_YET_RECRUITING

    Bristol, United Kingdom

    Contact

  • King's College Hospital

    RECRUITING

    London, United Kingdom

    Contact

  • Leeds General Infirmary

    RECRUITING

    Leeds, United Kingdom

    Contact

  • National Hospital for Neurology and Neurosurgery

    RECRUITING

    London, United Kingdom

    Contact

  • Princess Alexandra Eye Pavillion

    RECRUITING

    Edinburgh, United Kingdom

    Contact

  • Queen Elizabeth University Hospital

    RECRUITING

    Glasgow, United Kingdom

    Contact

  • Queen's Medical Centre

    RECRUITING

    Nottingham, United Kingdom

    Contact

  • Royal Hull Infirmary

    RECRUITING

    Hull, United Kingdom

    Contact

  • Royal Victoria Infirmary

    RECRUITING

    Newcastle, United Kingdom

    Contact

  • Southampton General Hospital

    RECRUITING

    Southampton, United Kingdom

    Contact

  • Southmead Hospital

    NOT_YET_RECRUITING

    Bristol, United Kingdom

    Contact

  • Sunderland Eye Infirmary

    RECRUITING

    Sunderland, United Kingdom

    Contact

  • The Queen Elizabeth Hospital

    RECRUITING

    Birmingham, United Kingdom

    Contact

  • University Hospital of Wales

    RECRUITING

    Cardiff, United Kingdom

    Contact

Conditions

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