Sarcoma study: does Anti-Nausea pill change chemo levels?

NCT ID NCT03514381

First seen Apr 28, 2026 · Last updated May 01, 2026 · Updated 1 time

Summary

This study looked at how the anti-nausea drug aprepitant changes the amount of the chemotherapy drug ifosfamide in the blood of people with soft tissue sarcoma. 59 patients receiving standard chemotherapy (doxorubicin and ifosfamide) had their ifosfamide levels measured during their first treatment cycle without aprepitant, and again during the second cycle with aprepitant. The goal was to see if aprepitant affects ifosfamide levels and to track any side effects.

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Contacts and locations

Locations

  • Institut Bergonie

    Bordeaux, 33076, France

  • Institut Regional Du Cancer de Montpellier (Icm)

    Montpellier, 34298, France

  • Institut Universitaire Du Cancer de Toulouse - Oncopole

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.