New hope for ALS patients: experimental drug shows promise in early trial
NCT ID NCT05508074
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 23 times
Summary
This study tested an experimental drug called IFB-088 added to the standard ALS medication riluzole in 51 people with bulbar-onset ALS (a form that first affects speech and swallowing). The goal was to see if the combination is safe and shows signs of slowing the disease. Participants took either IFB-088 plus riluzole or a placebo plus riluzole for 6 months, and researchers tracked their muscle function, breathing, and quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHM Hôpital La Timone Adultes SCE Maladies Neuromusculaires / SLA
Marseille, 13385, France
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CHU Bretonneau
Tours, 37044, France
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CHU de Nantes - Hôpital Laennec
Nantes, 44093, France
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CHU de Toulouse - Hôpital Pierre-Paul Riquet
Toulouse, 31059, France
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Centro Clinico NeMO per le Malattie Neuromuscolari
Gussago, 25064, Italy
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Hôpital Neurologique Pierre Wertheimer
Bron, 69677, France
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IRCSS Istituto Neurologico Carlo Besta
Milan, 20133, Italy
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Ospedale Civile Sant'Agostino Estense
Baggiovara, 41126, Italy
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Sant'Andrea Hospital Unit of Neuromuscular Disorders
Roma, 00189, Italy
Conditions
Explore the condition pages connected to this study.