New drug combo shows promise for untreated leukemia patients

NCT ID NCT02135133

First seen Mar 06, 2026 · Last updated May 15, 2026 · Updated 9 times

Summary

This study tested a combination of two drugs, idelalisib and ofatumumab, in 27 adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who had not received prior treatment. The goal was to see how well the drugs worked together to shrink or control the cancer. Researchers measured response rates and monitored side effects. The study was completed and aimed to improve outcomes compared to using either drug alone.

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Contacts and locations

Locations

  • Beth Isreal Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.