New hope for leukemia patients? early trial launches

NCT ID NCT06656494

Recruiting now Disease control Sponsor: Beijing InnoCare Pharma Tech Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new drug (ICP-248) combined with a standard medicine (azacitidine) in people with acute myeloid leukemia or myelodysplastic syndromes. The goal is to find a safe dose and see if the combo helps control the disease. About 266 adults who have not responded to prior treatment or are older and newly diagnosed will take part.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia myelodysplastic syndrome Myelodysplastic Syndromes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE MYELOGENOUS LEUKEMIA MYELODYSPLASTIC SYNDROMES (MDS)

Contacts and locations

Locations

Anhui Provincial Hospita
RECRUITING

Hefei, Anhui, 230001, China
Guangdong Provincial People's Hospital
RECRUITING

Guangzhou, Guangdong, 510030, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450000, China
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Nanfang Hospital Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510515, China
Peking University People's Hospital
RECRUITING

Beijing, Beijing Municipality, 100044, China
Royal Perth Hospital
RECRUITING

Perth, Western Australia, 6000, Australia
Shengjing Hospital of China Medical University
RECRUITING

Shengyang, Liaoning, 110004, China
Sichuan Provincial People's Hospital
RECRUITING

Chengdu, Sichuan, 610072, China
St Vincent's Hospital
RECRUITING

Sydney, New South Wales, 2010, Australia
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, 400042, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330006, China
The First Affiliated Hospital of Soochow University
RECRUITING

Suzhou, Jiangsu, 215006, China
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310012, China
The First Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130000, China
Tianjin People's Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300192, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430000, China
Yale University, Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06520, United States

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