Scientists launch Long-Term study to unravel mysterious immune condition

NCT ID NCT00867269

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 10 times

Summary

This study follows 950 people with idiopathic CD4+ lymphocytopenia (ICL), a rare condition where low CD4+ white blood cells raise infection risk. Researchers will track participants for up to 10 years, collecting medical history, blood samples, and infection data. The goal is to understand how ICL progresses and what causes it, without testing any new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal genetic or immune factors behind ICL, pointing toward future treatments.
What could go wrong
This is an observational study, not testing a treatment. It may not lead to direct therapies, and results depend on long-term follow-up.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.