Heart device study aims to reduce painful shocks with smarter pacing

NCT ID NCT05426785

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways of programming implantable defibrillators (ICDs) in 398 Japanese patients. One group uses early, multiple bursts of rapid pacing (ATP) to stop dangerous heart rhythms, while the other uses a longer detection time before pacing. The goal is to see which approach reduces the need for painful shocks and is safe. Results could help doctors set ICDs to work better for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Anti-tachycardia pacing (ATP) delivered by an implantable cardioverter defibrillator (ICD)
What this could lead to
If successful, this could lead to fewer painful shocks from ICDs, improving quality of life for patients at risk of dangerous heart rhythms.
What could go wrong
This is a mid-stage study in a specific population (Japanese patients), so results may not apply broadly. The intervention is a device setting change, not a new therapy, so the impact is incremental.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kokura Memorial Hospital

    Kitakyushu, Fukuoka, 8028555, Japan

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