New hope for HIV patients with aggressive lymphoma?
NCT ID NCT03220022
First seen Apr 19, 2026 · Last updated May 12, 2026 · Updated 5 times
Summary
This early-stage trial tested a combination of the targeted drug ibrutinib with standard chemotherapy (R-da-EPOCH) in 46 HIV-positive people with a type of lymphoma called diffuse large B-cell lymphoma. The main goals were to find the safest dose and check for side effects. The study is no longer recruiting, and results will help guide future treatment approaches.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Medical Center
Boston, Massachusetts, 02118, United States
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Memorial Hospital West
Pembroke Pines, Florida, 33028, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Nassau
Uniondale, New York, 11553, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Mount Sinai Hospital
New York, New York, 10029, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Pennsylvania Hospital
Philadelphia, Pennsylvania, 19107, United States
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Siteman Cancer Center at Washington University
St Louis, Missouri, 63110, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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UCSF Medical Center-Parnassus
San Francisco, California, 94143, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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University of Illinois College of Medicine - Chicago
Chicago, Illinois, 60612, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136, United States
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Virginia Mason Medical Center
Seattle, Washington, 98101, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.