Promising combo for High-Risk CLL falls short as trial ends early

NCT ID NCT03514017

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tested a two-drug combination—pembrolizumab and ibrutinib—in people with high-risk chronic lymphocytic leukemia (CLL) who had not yet received treatment. The goal was to see if the drugs could improve the body's immune function and shrink or control the cancer. Only 5 people enrolled before the trial was stopped early, so the results are limited.

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Contacts and locations

Locations

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.