Promising CLL combo trial halted early after enrolling just 5 patients
NCT ID NCT03514017
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 24 times
Summary
This study tested a two-drug approach—pembrolizumab (an immunotherapy) followed by ibrutinib—in people with previously untreated, high-risk chronic lymphocytic leukemia (CLL). The goal was to see if the combination could improve the body's immune function and shrink or control the cancer. Only 5 participants were enrolled before the trial was stopped early, so results are very limited.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States
Conditions
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