New drug combo aims to wipe out hidden myeloma cells after transplant

NCT ID NCT05434689

Ongoing Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jan 09, 2026 · Last updated May 14, 2026 · Updated 17 times

Summary

This study tests whether adding iberdomide (taken as a pill) together with other drugs can clear tiny amounts of multiple myeloma that remain after a stem cell transplant. About 80 adults with newly diagnosed myeloma who still have detectable disease after transplant will receive these combinations. The goal is to turn the cancer undetectable and keep it that way, improving long-term control.

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Contacts and locations

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Locations

Duke University

Durham, North Carolina, 27710, United States
Ohio State University Medical College

Columbus, Ohio, 43210, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States
University of Wisconsin

Madison, Wisconsin, 53705, United States
Vanderbilt University Medical College

Nashville, Tennessee, 37232, United States

Conditions

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MULTIPLE MYELOMA