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Decoding low sodium: a new tool to guide safer treatment

NCT ID NCT00541944

Knowledge-focused Sponsor: University of Wuerzburg Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This study aims to create a practical algorithm to help doctors classify the different causes of hyponatremia, a condition where blood sodium levels are abnormally low. The trial will involve adults with severe hyponatremia and will test whether a structured approach can accurately identify the underlying cause. The goal is to enable faster, safer, and more targeted treatment for this potentially dangerous condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could provide doctors with a practical tool to quickly identify the cause of low blood sodium, leading to safer and more effective treatment decisions.
What could go wrong
This is an early-stage study focused on developing a diagnostic approach, not a treatment. The algorithm may not prove accurate or easy to use in all clinical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

138 people

The number who actually took part.

Start date

Apr 2007

Finished

Dec 2008

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients treated in an University Hospital in Germany

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * hypoosmolar hyponatremia with serum sodium concentration ≤129 mmol/l and serum osmolality ≤ 280 mosm/kg; * age \> 18 years; * letter of agreement. Exclusion Criteria: * gravidity and lactation; * restricted decision-making-ability

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Conditions

The condition(s) this trial relates to.

disease Hyponatremia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hyponatremia

Contacts and locations

Locations

  • University of Wuerzburg

    Würzburg, 97080, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.