Gut bugs linked to bone loss in parathyroid disease
NCT ID NCT04948671
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether the types of bacteria in the gut can predict bone loss in people with primary hyperparathyroidism, a condition where the parathyroid glands produce too much hormone. Researchers planned to analyze gut bacteria and immune system markers in 25 patients with and without bone problems. The goal was to see if gut bacteria could be used as a screening tool to identify those at risk, but the study was terminated early.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could show that analyzing gut bacteria helps identify which patients with primary hyperparathyroidism will develop bone loss, potentially leading to new prevention strategies.
- What could go wrong
- This is a small, terminated observational study with only 25 participants. It does not test any treatment, so any findings would need much larger studies to confirm.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Patrizia D'amelio
Lausanne, Switzerland, 1012, Switzerland
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