Gut bugs linked to bone loss in parathyroid disease

NCT ID NCT04948671

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether the types of bacteria in the gut can predict bone loss in people with primary hyperparathyroidism, a condition where the parathyroid glands produce too much hormone. Researchers planned to analyze gut bacteria and immune system markers in 25 patients with and without bone problems. The goal was to see if gut bacteria could be used as a screening tool to identify those at risk, but the study was terminated early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could show that analyzing gut bacteria helps identify which patients with primary hyperparathyroidism will develop bone loss, potentially leading to new prevention strategies.

What could go wrong

This is a small, terminated observational study with only 25 participants. It does not test any treatment, so any findings would need much larger studies to confirm.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

primary hyperparathyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • Patrizia D'amelio

    Lausanne, Switzerland, 1012, Switzerland