New Short-Course radiation after prostate surgery shows promise
NCT ID NCT03570827
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 38 times
Summary
This phase II trial tested a shorter, higher-dose radiation schedule (hypofractionation) in 53 men with high-risk prostate cancer after their prostate was removed. The goal was to see if this approach could control cancer with fewer side effects than standard radiation. Participants also received hormone therapy. The study is complete, and results focus on how long men stayed free of cancer recurrence.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hypofractionated radiation therapy and androgen suppression therapy
What this could lead to
If successful, this could offer a shorter, more convenient radiation schedule after prostate surgery with fewer side effects while still controlling cancer.
What could go wrong
This is a small, early-phase trial (53 people) with no comparison group, so results may not apply broadly. Side effects from radiation and hormone therapy are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.