Salt water infusion could save lives after severe head trauma
NCT ID NCT07319208
First seen Jan 07, 2026 · Last updated May 02, 2026 · Updated 18 times
Summary
This study tests whether giving a concentrated salt solution (hypertonic saline) early after a severe traumatic brain injury can help more people survive and regain independence in daily activities. About 760 patients in intensive care will receive either the salt solution or standard care. The goal is to reduce brain swelling and improve outcomes at 6 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP-HM
NOT_YET_RECRUITINGMarseille, France
Contact Email: •••••@•••••
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CH de Annecy Genevois
NOT_YET_RECRUITINGÉpagny, France
Contact Email: •••••@•••••
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CHRU de Tours
NOT_YET_RECRUITINGTours, France
Contact Email: •••••@•••••
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CHU Caen Normandie
NOT_YET_RECRUITINGCaen, France
Contact Email: •••••@•••••
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CHU Henri Mondor APHP
NOT_YET_RECRUITINGCréteil, France
Contact Email: •••••@•••••
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CHU Lariboisière, AP-HP
NOT_YET_RECRUITINGParis, France
Contact Email: •••••@•••••
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CHU d'Angers
NOT_YET_RECRUITINGAngers, France
Contact Email: •••••@•••••
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CHU de Brest
NOT_YET_RECRUITINGBrest, France
Contact Email: •••••@•••••
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CHU de Clermont- Ferrand
NOT_YET_RECRUITINGClermont-Ferrand, France
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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CHU de Grenoble
NOT_YET_RECRUITINGGrenoble, France
Contact Email: •••••@•••••
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CHU de Lille
NOT_YET_RECRUITINGLille, France
Contact Email: •••••@•••••
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CHU de Nancy
NOT_YET_RECRUITINGNancy, France
Contact Email: •••••@•••••
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CHU de Nantes
RECRUITINGNantes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Nice
NOT_YET_RECRUITINGNice, France
Contact Email: •••••@•••••
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CHU de Poitiers
NOT_YET_RECRUITINGPoitiers, France
Contact Email: •••••@•••••
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CHU de Rennes
NOT_YET_RECRUITINGRennes, France
Contact Email: •••••@•••••
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CHU de Rouen
NOT_YET_RECRUITINGRouen, France
Contact Email: •••••@•••••
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CHU de St- Etienne
NOT_YET_RECRUITINGSaint-Etienne, France
Contact Email: •••••@•••••
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CHU de Strasbourg
NOT_YET_RECRUITINGStrasbourg, France
Contact Email: •••••@•••••
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CHU de Toulouse
NOT_YET_RECRUITINGToulouse, France
Contact Email: •••••@•••••
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GHU Paris Cité
NOT_YET_RECRUITINGParis, France
Contact Email: •••••@•••••
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HCL
NOT_YET_RECRUITINGLyon, France
Contact Email: •••••@•••••
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Hôpital BEAUJON APHP
NOT_YET_RECRUITINGClichy, France
Contact Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.