New MRI dye could spot aggressive brain tumors without surgery

NCT ID NCT06014905

Recruiting now Diagnosis Sponsor: Charlie Wang, MD, PhD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This early study tests a special MRI technique that uses a substance called hyperpolarized pyruvate to see how active a meningioma brain tumor is. About 50 adults with known or suspected meningioma will get an IV of this substance before an MRI scan. The goal is to see if this method can safely and reliably tell aggressive tumors from slow-growing ones, which could help avoid unnecessary biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hyperpolarized carbon C 13 pyruvate
What this could lead to: If successful, this imaging method could help doctors identify aggressive meningiomas without needing a biopsy, guiding treatment decisions more quickly.
What could go wrong: This is a very early pilot study with only 50 participants, so it may not work for everyone. The technique is still experimental and not yet proven to be better than standard scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MENINGIOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

meningioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENINGIOMA

Contacts and locations

Show contact details

Locations

University of California, San Francisco
RECRUITING

San Francisco, California, 94143, United States

Contact Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.