Tailoring sickle cell drug doses: a new hope for nigerian patients
NCT ID NCT07543289
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how genetic differences affect the way Nigerian sickle cell patients respond to hydroxyurea, a common treatment. Researchers will monitor 100 patients to build a computer model that predicts the best dose for each person. The goal is to reduce side effects and improve outcomes like fewer pain crises.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hydroxyurea
What this could lead to
If successful, this could lead to personalized hydroxyurea dosing guidelines for Nigerian sickle cell patients, making treatment safer and more effective.
What could go wrong
This is an early-stage observational study with only 100 participants, so results may not apply to all patients. The models need further validation before clinical use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Obafemi Awolowo University Teaching Hospital Complex
Ile-Ife, Osun State, 220282, Nigeria
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••