Can a lupus drug protect kidneys in IgA disease? new trial aims to find out.

NCT ID NCT06350630

First seen Jun 16, 2026 · Last updated Jun 18, 2026 · Updated 1 time

Summary

This study tests whether hydroxychloroquine, a drug already used for lupus, can slow kidney function decline in people with IgA nephropathy (Berger's disease). About 334 adults with biopsy-confirmed IgA nephropathy and high protein in their urine will receive either hydroxychloroquine or a placebo for up to 2 years. The goal is to see if the drug helps preserve kidney function and reduce protein leakage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP-HM Hôpital de la Conception

    RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP Hôpital Bichat

    RECRUITING

    Paris, 75018, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • APHP Hôpital de Tenon

    RECRUITING

    Paris, 75020, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Gabriel Montpied

    RECRUITING

    Clermont-Ferrand, 63000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Lyon Sud

    RECRUITING

    Pierre-Bénite, 69495, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Saint-Etienne

    RECRUITING

    Saint-Etienne, 42055, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospices Civils de Lyon

    RECRUITING

    Lyon, 69437, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

IgA glomerulonephritis proteinuria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.