Premie steroid study: could a common drug raise blood pressure years later?
NCT ID NCT05451264
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows up on 52 children, now aged 7 to 13, who were born very prematurely and received either hydrocortisone or a placebo in the PREMILOC trial. Researchers are measuring their blood pressure, pulse wave velocity, and other heart-related markers to see if the steroid affected their cardiovascular health. The goal is to understand long-term risks, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydrocortisone
What this could lead to
If it works, this could help doctors understand whether hydrocortisone given to premature babies raises their risk of high blood pressure later in life.
What could go wrong
This is a small, observational follow-up study, not a new treatment trial. It can only show a link, not prove cause and effect, and results may not apply to all premature infants.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Robert Debre Hospital
Paris, 75019, France