Drink up? study tests if water intake changes how your body burns fuel

NCT ID NCT07298863

Recruiting now Knowledge-focused Sponsor: PepsiCo Global R&D Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how being well-hydrated or dehydrated affects the way your body uses fat and carbohydrates for energy, both at rest and during light to moderate cycling. Researchers will track 74 healthy adults, including women with normal menstrual cycles, to see if hydration status influences metabolic flexibility—a key factor linked to type 2 diabetes. Participants will follow specific hydration plans and perform exercise tests to measure fuel use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help explain how drinking enough water affects the body's ability to switch between burning fat and carbs, which may relate to diabetes risk.
What could go wrong: This is an early-stage observational study with only 74 participants, so results may not apply broadly. It looks at short-term effects, not long-term health outcomes.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYDRATION STATUS SUBSTRATE METABOLISM DURING EXERCISE

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Gatorade Sports Science Institute
RECRUITING

Valhalla, New York, 10595, United States

Contact Email: •••••@•••••

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