New hybrid heart procedure could offer better rhythm control for heart failure patients

NCT ID NCT05411614

First seen Nov 18, 2025 · Last updated May 29, 2026 · Updated 23 times

Summary

This study tests if a two-step hybrid ablation procedure works better than standard catheter ablation for people with persistent atrial fibrillation (an irregular heartbeat) and heart failure. About 120 adults with enlarged hearts and reduced pumping function will be randomly assigned to one of the two procedures. The goal is to see which approach better prevents long-term heart rhythm problems and improves heart function.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ashford & St Peters Hospital NHS Trust

    RECRUITING

    Chertsey, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cromwell Hospital

    ACTIVE_NOT_RECRUITING

    London, United Kingdom

  • Epsom General Hospital

    RECRUITING

    Epsom, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Surrey County Hospital

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St Anthonys Hospital

    ACTIVE_NOT_RECRUITING

    London, United Kingdom

  • St Georges University of London

    RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

  • St Georges at Kingston Hospital

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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