Could a simple gel boost gum surgery results?

NCT ID NCT07529340

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Gum recession exposes tooth roots, causing sensitivity and cosmetic concerns. Standard surgery (CAF + SCTG) covers the root, but healing can be slow. This trial tests whether adding a hyaluronic acid gel (hyaDENT BG®) to the surgery improves root coverage and recovery. Thirty-four adults with single gum recession defects will be randomly assigned to surgery with or without the gel, and followed for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cross-linked hyaluronic acid gel (hyaDENT BG®)
What this could lead to
If it works, this could make gum surgery more effective at covering exposed roots and reduce pain or healing time.
What could go wrong
This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. The gel is an add-on, not a replacement for surgery, and may not provide significant benefit.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CEPI - Clinical Center for Periodontology and Implantology

    Porto, Porto District, 4350-110, Portugal

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