Can a Brain-Bleed drug protect memory after surgery?

NCT ID NCT05560373

NEW Not yet recruiting Disease control Sponsor: Wanbangde Pharmaceutical Group Co., LTD Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This study tests whether huperzine A, an injected drug, can help prevent or reduce memory and thinking problems that often follow surgery for a bleeding brain aneurysm. Adults aged 18-70 who had an aneurysm bleed and underwent endovascular or surgical treatment will receive either huperzine A or standard care. Researchers will compare cognitive function and mood over time to see if the drug offers any benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Huperzine A injection
What this could lead to: If effective, huperzine A could offer a way to reduce long-term memory and thinking problems after brain aneurysm surgery.
What could go wrong: This is a small pilot study, so results may not apply broadly. The drug may not improve cognition and could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired aneurysmal subarachnoid hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE COGNITIVE DYSFUNCTION IN PATIENTS WITH ANEURYSMAL SUBARACHNOID HEMORRHAGE

Contacts and locations

Locations

Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

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