Hunter syndrome immune study pulled before it began
NCT ID NCT05494593
First seen Jan 04, 2026 · Last updated May 06, 2026 · Updated 24 times
Summary
This study aimed to see if a combination of immune-suppressing drugs could prevent the body from making antibodies that block the enzyme therapy ELAPRASE in boys with Hunter syndrome who had never been treated before. The plan was to give rituximab, methotrexate, and intravenous immunoglobulin alongside ELAPRASE for up to 104 weeks. However, the study was withdrawn before enrolling any participants, so no results are available.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ann and Robert H Lurie Childrens Hospital of Chicago
Chicago, Illinois, 60611, United States
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Children's Hospital and Research Center at Oakland
Oakland, California, 94609, United States
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Children's Hospitals and Clinics of Minnesota
Minneapolis, Minnesota, 55404, United States
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NewYork-Presbyterian Morgan Stanley Children's Hospital
New York, New York, 10032, United States
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Phoenix Childrens Hospital
Phoenix, Arizona, 85016, United States
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Rady Childrens Hospital San Diego - PIN
San Diego, California, 92123, United States
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The Cleveland Clinic Foundation
Twinsburg, Ohio, 44087, United States
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The Lundquist Institute for BioMedical Innovation at Harbor-UCLA Medical Center
Torrance, California, 90502, United States
Conditions
Explore the condition pages connected to this study.