New bladder gel could help patients avoid bladder removal surgery
NCT ID NCT07468851
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new treatment called HS-10566, a gel that delivers the chemotherapy drug gemcitabine directly into the bladder. It is for people with high-risk non-muscle-invasive bladder cancer who cannot or choose not to have their bladder removed. The trial will check if the treatment is safe, tolerable, and effective at controlling the cancer. About 180 adults will take part in this early-phase study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HS-10566 (a gel that delivers the chemotherapy drug gemcitabine directly into the bladder)
- What this could lead to
- If successful, this could offer a bladder-sparing treatment option for patients with high-risk bladder cancer who cannot or choose not to have their bladder removed.
- What could go wrong
- This is an early-phase trial (Phase 1/2) with a small number of participants, so safety and effectiveness are not yet proven. The treatment may not work for everyone and could cause side effects from the chemotherapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nanjing Drum Tower Hospital
Nanjing, 210008, China
-
Peking University First Hospital
Beijing, 100034, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple blood or urine test spot bladder cancer earlier?
- Bladder cancer drug delivered directly: a new hope for BCG failures
- New bladder cancer drug enters first human tests
- Urine test may spare bladder cancer patients from unnecessary second surgery
- New pill could fight bladder cancer when standard therapy fails
- New drug combo offers hope for bladder cancer patients who failed standard therapy