New pill aims to tame Hormone-Driven high blood pressure
NCT ID NCT07470983
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called HRS-1780 in 60 adults with primary aldosteronism, a condition where the adrenal glands make too much of a hormone that raises blood pressure. Participants will receive either HRS-1780 or a placebo to see if the drug safely lowers blood pressure and controls hormone levels. The trial is double-blind, meaning neither patients nor doctors know who gets the real drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HRS-1780 (a drug taken as a tablet)
- What this could lead to
- If it works, this could offer a new treatment option to control blood pressure and hormone levels in people with primary aldosteronism.
- What could go wrong
- This is an early Phase 2 trial with only 60 people, so results may not apply broadly. The drug may not work better than placebo or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400016, China
-
The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, 450052, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New scan could replace risky vein test for Hormone-Driven high blood pressure
- New screening strategy could speed diagnosis of inherited aldosteronism
- Alcohol injection into adrenal tumors may offer surgery-free blood pressure control
- Sharper blood test could uncover hidden cause of high blood pressure
- New drug may offer safer option for Hormone-Driven high blood pressure