New pill aims to tame Hormone-Driven high blood pressure

NCT ID NCT07470983

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called HRS-1780 in 60 adults with primary aldosteronism, a condition where the adrenal glands make too much of a hormone that raises blood pressure. Participants will receive either HRS-1780 or a placebo to see if the drug safely lowers blood pressure and controls hormone levels. The trial is double-blind, meaning neither patients nor doctors know who gets the real drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HRS-1780 (a drug taken as a tablet)

What this could lead to

If it works, this could offer a new treatment option to control blood pressure and hormone levels in people with primary aldosteronism.

What could go wrong

This is an early Phase 2 trial with only 60 people, so results may not apply broadly. The drug may not work better than placebo or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, 400016, China

    Contact

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 450052, China

    Contact