New HPV vaccine combo shows promise against tough cancers

NCT ID NCT04432597

First seen Dec 10, 2025 · Last updated May 10, 2026 · Updated 21 times

Summary

This study tests an HPV vaccine (PRGN-2009) alone or combined with a drug called M7824 in adults with HPV-positive cancers like cervical, anal, and throat cancers. The goal is to find a safe dose and see if the combination boosts the immune system's attack on tumors. Participants receive injections and infusions over up to a year, with long-term follow-up.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.