Triple threat: vaccine, immunotherapy, and Chemo-Radiation take on HPV head and neck cancer

NCT ID NCT04369937

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 25 times

Summary

This study tests a new treatment for a type of head and neck cancer caused by HPV. It combines a vaccine that targets the cancer cells, an immunotherapy drug (pembrolizumab), and standard chemo-radiation. The goal is to see if this combination can better control the cancer and prevent it from coming back. The study involves 18 adults with newly diagnosed, intermediate-risk disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.