Herbal drink may soothe radiation mouth pain in cancer patients

NCT ID NCT07311772

Recruiting now Symptom relief Sponsor: Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether Houyanqing Oral Liquid, a Chinese herbal mix, can prevent or reduce severe mouth sores caused by radiation therapy in 386 nasopharyngeal cancer patients. Participants take the liquid four times daily during radiation, alongside standard care. The study aims to see if fewer patients develop grade 2 or worse mouth sores, and if their quality of life improves.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Houyanqing Oral Liquid (a Chinese herbal preparation)
What this could lead to: If it works, this could offer a new option to reduce painful mouth sores during radiation, improving quality of life for nasopharyngeal cancer patients.
What could go wrong: This is a single phase 3 trial with a herbal product, so results may not be widely applicable. The herbal mixture may cause side effects or interact with other treatments.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced oral mucositis nasopharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NASOPHARYNGEAL CANCINOMA (NPC) RADIATION INDUCED ORAL MUCOSITIS

Contacts and locations

Locations

Affiliated Cancer Hospital & Institute of Guangzhou Medical University
RECRUITING

Guangzhou, Guangdong, 510095, China
Cancer Hospital Chinese Academy of Medical Science
RECRUITING

Beijing, Beijing Municipality, 100021, China
Cancer Hospital of Guangxi Medical University
RECRUITING

Nanning, Guangxi, 530021, China
Cancer Hospital of Shantou University Medical College
RECRUITING

Shantou, Guangdong, 515041, China
Eye & ENT Hospital of Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200031, China
Fifth Affiliated Hospital of Sun Yat-sen University
RECRUITING

Zhuhai, Guangdong, 519000, China
Fujian Medical University Cancer Hospital
RECRUITING

Fuzhou, Fujian, 350014, China
Hunan Cancer Hospital
RECRUITING

Changsha, Hunan, 410013, China
Sun Yat-sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, 510060, China
The First Affiliated Hospital of Kunming Medical University
RECRUITING

Kunming, Yunnan, 650032, China
The First People's Hospital of Changzhou
RECRUITING

Changzhou, Jiangsu, 213003, China
West China Hospital of Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China
Wuzhou Red Cross Hospital
RECRUITING

Wuzhou, Guangxi, 543002, China
Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410008, China
Yunnan Cancer Hospital
RECRUITING

Kunming, Yunnan, 650118, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhengjiang, 310022, China

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