Hormone shield: could progesterone or testosterone guard against Drug-Induced heart risks?

NCT ID NCT04675788

Completed Knowledge-focused Sponsor: Indiana University Source: ClinicalTrials.gov ↗

First seen Mar 31, 2026 · Last updated Jun 13, 2026 · Updated 10 times

Summary

This study looked at whether taking progesterone (in women) or testosterone (in men) could reduce dangerous changes in heart rhythm caused by certain medications. 73 healthy older adults (postmenopausal women and men 65+) took either the hormone or a placebo, then received a small dose of a heart-rhythm-altering drug. Researchers measured heart electrical activity to see if the hormones offered protection. The goal was to find new ways to prevent drug-induced heart problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LONG QT SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Indiana Clinical Research Center

Indianapolis, Indiana, 46202, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Purdue University

Indianapolis, Indiana, 46202, United States

Conditions

Explore the condition pages connected to this study.

ABNORMALITIES, DRUG-INDUCED ABNORMALITIES, DRUG-INDUCED LONG QT SYNDROME LONG QT SYNDROME