Exercise plus hormone therapy may cut heart risk in menopause
NCT ID NCT05831709
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether combining hormone replacement therapy with a supervised exercise program can improve body composition, heart health, and insulin sensitivity in postmenopausal women. Researchers will follow 390 women over 24 weeks, measuring changes in cardiovascular risk, insulin sensitivity, and body composition. The goal is to see if this combination offers better health outcomes than either approach alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hormonal substitution therapy (hormone replacement therapy) and supervised exercise program
What this could lead to
If successful, this could show that combining hormone therapy with exercise helps manage menopause-related health risks like heart disease and diabetes.
What could go wrong
This is an early-stage observational study, not a treatment trial. Results may not lead to a new therapy, and individual responses to hormones and exercise vary.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ghent University Hospital - Women's Clinic
RECRUITINGGhent, 9000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••