New machine perfusion technique cuts early liver failure risk in transplants

NCT ID NCT03929523

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 36 times

Summary

This study tested a method called HOPE, which gently pumps oxygenated cold fluid through donor livers before transplant. It included 266 adults receiving a liver from an older or higher-risk donor. The goal was to see if HOPE reduces early liver problems after surgery compared to standard cold storage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LIVER TRANSPLANTATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • APHP - Pitié Salpétrière

    Paris, 75013, France

  • CHU Grenoble Alpes - Department of HPB surgery and liver transplantation

    Grenoble, 38000, France

  • Department of HPB surgery and liver transplantation Beaujon University Hospital

    Clichy, 92210, France

  • Department of HPB surgery and liver transplantation Claude Huriez University Hospital

    Lille, 59037, France

  • Department of HPB surgery and liver transplantation Paul Brousse University Hospital

    Villejuif, 94804, France

  • Department of HPB surgery and liver transplantation Pontchaillou University Hospital

    Rennes, 35033, France

  • Hospices Civils de Lyon

    Lyon, 69004, France

  • Hôpital Hautepierre - Department of HPB surgery and liver transplantation

    Strasbourg, 67200, France

Conditions

Explore the condition pages connected to this study.