Nightly oxygen may ease sickle cell crisis in pregnancy

NCT ID NCT02813850

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving oxygen at home during the night could prevent severe pain episodes and other complications in pregnant women with sickle cell disease. 178 pregnant women took part, using an oxygen device for 4 hours each night. The goal was to see if this simple approach could reduce hospital visits and protect both mother and baby.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxygen therapy
What this could lead to
If it works, this could offer a simple, low-cost way to reduce dangerous pain crises and other complications during pregnancy for women with sickle cell disease.
What could go wrong
The trial is completed but results are not yet widely reported, so it is unclear if the oxygen therapy truly helped. Also, the treatment requires a device at home and may not be practical for everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker Enfants-Malades (Public Hospitals of Paris)

    Paris, Paris, 75015, France

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