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Which laser frequency works best for prostate surgery?

NCT ID NCT06531473

Disease control Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial compares three different laser frequency settings (40, 50, and 60 Hz) used during a procedure called HoLEP, which treats enlarged prostates causing bothersome urinary symptoms. Men aged 18-89 undergoing HoLEP will be randomly assigned to one of the laser settings on the day of surgery. The goal is to see if one setting leads to better surgical outcomes, such as shorter operation time or fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Holmium laser enucleation of the prostate (HoLEP) with different laser frequency settings (40, 50, or 60 Hz)
What this could lead to
If successful, this could help surgeons choose the best laser setting for HoLEP, potentially improving outcomes and recovery for men with enlarged prostates.
What could go wrong
This is a single-center trial, and results may not apply to all patients or hospitals. Different laser settings might not lead to significant differences in outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

278 people

The number who actually took part.

Started

Mar 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 89 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males 18-89 who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms, that are typically caused by enlarged prostates Exclusion Criteria: * Prostates measurements over 200g * Patients who lack decisional capacity * Patients who are non-english speakers

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Conditions

The condition(s) this trial relates to.

urethral obstruction urinary system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Prostate obstruction Urologic diseases

Contacts and locations

Locations

  • Northwestern Medicine

    Chicago, Illinois, 60611, United States

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