Could a simple supplement boost muscle strength before lung transplant?

NCT ID NCT07660991

Completed Disease control Sponsor: Okan University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether adding a dietary supplement called hydroxymethylbutyrate (HMB) to standard pulmonary rehabilitation helps lung transplant candidates improve muscle mass, strength, and overall health. Participants are adults aged 40-50 who are on the waiting list for a lung transplant. Half will receive HMB for 8 weeks alongside rehab and diet therapy, while the other half receive only rehab and diet therapy. The goal is to see if HMB can better prepare patients for surgery and recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hydroxymethylbutyrate (HMB)
What this could lead to: If it works, this could help lung transplant candidates maintain muscle mass and function before surgery, potentially improving recovery and quality of life.
What could go wrong: This is a small, early-stage study with only 30 participants, so results may not apply to everyone. HMB is generally safe but may not provide significant benefits over rehabilitation alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUN TRANSPLANT CANDIDATES LUNG TRANSPLANTATION PULMONER REHABILITATION

Contacts and locations

Locations

Koşuyolu Yüksek Ihtisas Eğitim Ve Araştırma Hastanesi

Istanbul, Kartal, 34865, Turkey (Türkiye)

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